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Acta Anaesthesiol Scand · Jun 1983
Comparative StudyIntradermal histamine release by 3 muscle relaxants.
- E N Robertson, L H Booij, R J Fragen, and J F Crul.
- Acta Anaesthesiol Scand. 1983 Jun 1; 27 (3): 203-5.
AbstractThe induration and redness caused by intradermal injections of equipotent doses of atracurium, vecuronium and d-tubocurarine were measured in six healthy, male volunteers. Atracurium and d-tubocurarine were almost indistinguishable in their reactions. Vecuronium caused a significantly smaller response than both atracurium and d-tubocurarine. We therefore suggest that of these three drugs, vecuronium may cause the least histamine release and is, perhaps, the drug of choice in patients with a history of asthma or allergy.
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