• Am. J. Med. · Feb 1991

    Review Case Reports

    Tissue-plasminogen activator for pulmonary embolism resulting in shock: two case reports and discussion of the literature.

    • J P Mitchell and E P Trulock.
    • Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110.
    • Am. J. Med. 1991 Feb 1; 90 (2): 255-60.

    AbstractTwo patients with significant relative contraindications to fibrinolysis, and with refractory shock caused by acute pulmonary embolism, who were successfully treated with recombinant tissue-type plasminogen activator (rt-PA) are reported. The role of rt-PA in the management of pulmonary embolism is discussed, and pertinent literature is reviewed.

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