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Obstetrics and gynecology · Nov 2019
Case ReportsExtracorporeal Therapies for Amniotic Fluid Embolism.
- Julien Viau-Lapointe and Niall Filewod.
- Département de Médecine, Hôpital Maisonneuve-Rosemont, Université de Montréal, Montréal, Québec, the Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada.
- Obstet Gynecol. 2019 Nov 1; 134 (5): 989-994.
BackgroundAmniotic fluid embolism (AFE) is a catastrophic disease with significant mortality. Because the cardiopulmonary dysfunction associated with AFE is self-limited, the disease could be well suited to the use of extracorporeal therapies.CaseA woman progressed into cardiac arrest immediately after an elective cesarean delivery. Owing to severe hypoxemia and hypotension, AFE was suspected and peripheral venoarterial extracorporeal membrane oxygenation was quickly initiated. Subsequent evolution was complicated by intrabdominal bleeding, which required massive transfusion and multiple surgeries. The patient recovered well, with a healthy newborn. We have identified 19 similar cases in the literature and present their outcomes as a series.ConclusionExtracorporeal therapies can support severely ill women affected by AFE and could be considered even in the presence of disseminated intravascular coagulation and bleeding.
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