• Chirojit Mukherjee, Joerg Ender, Frederik Hein, David Holzhey, Lehmkuhl Lukas, Meinhard Mende, and Udo X Kaisers.
• Department of Anaesthesiology and Intensive Care Medicine II, Heartcentre, University of Leipzig, Leipzig, Germany. chirojit.mukherjee@med.uni-leipzig.de
• J. Cardiothorac. Vasc. Anesth.. 2013 Aug 1;27(4):654-9.

ObjectiveTransapical aortic valve implantation (TAVI) may lead to obstruction of coronary arteries during deployment. To prevent this, it is essential to determine the distance of the coronary ostium to the aortic annulus prior to valve placement. Multidetector computed tomography (MDCT) commonly is used to determine these measurements, but even marginal exposure to contrast agents can result in acute kidney injury in this high-risk group of multi-morbid patients. The aim of the study was to determine the feasibility of real-time 3D transesophageal echocardiography (RT 3D TEE) as the first-choice technique for noninvasive evaluation of the coronary ostium during TAVI.DesignRetrospective study.SettingUniversity hospital.InterventionsFifty patients underwent MDCT the evening before surgery. RT 3D TEE was performed intraoperatively before valve deployment. The dataset from both of these examinations was digitally stored and evaluated. MDCT was performed in nonanesthetized patients; however, in the RT 3D TEE group, general anesthesia was established.Measurements And Main ResultsThe distances from the right coronary artery and the left coronary artery ostium were measured retrospectively. Bland-Altman Plots and linear regression analysis showed excellent correlation between the 2 methodologies; intraobserver and interobserver variance were calculated using analysis of variance. Krippendorff's α indicated excellent agreement between the 2 observers (0.96 and 0.98) as well as between RT 3D TEE and MDCT (0.97 and 0.98).ConclusionsThe observations showed that RT 3D TEE reliably can measure the coronary ostium distance from the aortic annulus. It is feasible and an alternative method for evaluating these measurements and thereby preventing contrast exposure during MDCT, which may jeopardize the safety of patients with pre-existing renal disease.Copyright © 2013 Elsevier Inc. All rights reserved.

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