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Int. J. Tuberc. Lung Dis. · Oct 2011
Screening and follow-up of children exposed to tuberculosis cases, Luanda, Angola.
- I Fortunato and C Sant'Anna.
- Department of Infectious Diseases, Federal University of Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.
- Int. J. Tuberc. Lung Dis. 2011 Oct 1; 15 (10): 1359-61.
AbstractThis prospective study enrolled children aged < 5 years with reported contact with adult tuberculosis (TB) patients in Angola. The study sample consisted of 124 children: 70 (56.5%) were active TB cases, 22 (17.7%) had latent TB infection (LTBI) and 32 (25.8%) were TB-exposed; 14 (20%) were human immunodeficiency virus positive. After 6 months of follow-up, 31.8% of the LTBI cases had evolved to active TB and 9.4% of the non-infected children had developed active TB. The strategy of simultaneous chest X-ray and TB skin test used in this study was effective; despite this protocol, however, 31.8% LTBI children developed active TB.
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