• Theresa Elder, Tiffany Ejikeme, Peter Felton, Alankrita Raghavan, James Wright, Christina Huang Wright, Xiaofei Zhou, Kelsey Duncan, Martha Sajatovic, and Tiffany Hodges.
• Department of Neurological Surgery, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
• World Neurosurg. 2020 Jun 1; 138: e361-e369.

BackgroundRecent literature has shown significant differences in meningioma incidence among different races, but minimal conclusive data exist on the role of race and ethnicity in overall survival for patients with high-grade intracranial meningioma. We conducted a systematic review to investigate the impact of race and ethnicity on survival in patients with high-grade intracranial meningioma.MethodsA systematic literature review was conducted for studies using Ovid, PubMed, Cochrane, Embase, and Scopus databases. Databases were queried for the following: Meningioma AND [Ethnic OR Demography, OR African American OR Arab OR Hispanic OR Asian, OR White OR race OR racial] AND [survival OR survival analysis OR survival rate OR treatment outcome OR Survivor OR Outcome].ResultsA literature search yielded a total of 412 abstracts, which were screened according to criteria that were determined a priori, and a total of 129 full-text articles were reviewed. Four articles were included in the final analysis, reporting on a total of 13,424 patients. Three studies saw an overall survival benefit in White non-Hispanics compared with Black non-Hispanics, and 1 reported a survival benefit in White non-Hispanics and Black non-Hispanics among patients who received gross total resection. One study additionally reported an increased likelihood of White patients receiving gross total resection when compared with non-White patients.ConclusionsThe limited data available suggest that White patients have improved measures of survival compared with nonw-White patients, for reasons that are likely complex and multifactorial. Further studies are needed to explore these survival differences seen.Copyright © 2020 Elsevier Inc. All rights reserved.

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