• Katsunori Shijo, Sodai Yoshimura, Fumi Mori, Shun Yamamuro, Koichiro Sumi, Hideki Oshima, and Atsuo Yoshino.
• Department of Neurological Surgery, Nihon University School of Medicine, Tokyo, Japan.
• World Neurosurg. 2020 Jun 1; 138: 153-157.

BackgroundPituitary apoplexy is an acute clinical syndrome caused by infarction and/or hemorrhage of pituitary adenoma, which typically presents with severe headache, visual deterioration, and endocrine abnormalities. However, temporal lobe seizure (and temporal lobe epilepsy) has not been viewed as a symptom of pituitary apoplexy in the literature.Case DescriptionTo elucidate further such a rare complication of temporal lobe seizure, we describe here the rare clinical manifestations of a 55-year-old previously healthy man with pituitary apoplexy harboring headache, combined palsies involving cranial nerves III to VI, endocrinologic disturbances, and temporal lobe seizure. In addition, we discuss the temporal lobe seizure (and temporal lobe epilepsy) associated with pituitary adenoma based on the literature.ConclusionsAlthough further accumulation of clinical data is needed, we would like to emphasize the importance of recognition of temporal lobe seizure caused by pituitary apoplexy, and to suggest that early surgery could be considered as an option in patients displaying such a rare complication.Copyright © 2020 Elsevier Inc. All rights reserved.

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