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Internal medicine journal · Oct 2005
ReviewCautionary tales in the clinical interpretation of therapeutic trial reports.
- I A Scott and P B Greenberg.
- Princess Alexandra Hospital, Brisbane, Australia. ian_scott@health.qld.gov.au
- Intern Med J. 2005 Oct 1; 35 (10): 611-21.
AbstractPractising clinicians are assailed daily with reports of new therapeutic clinical trials. The evidence-based medicine movement has developed critical appraisal methods for assessing the validity and impact of such studies. However, challenges persist in regards to the appropriate interpretation and application of trial results within everyday clinical settings. Using selected examples from recently published literature, we illustrate 15 cautionary themes for translating research evidence from therapeutic trials into clinical practice.
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