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Pediatric emergency care · Jul 2021
Treatment Outcomes of Pediatric Status Epilepticus in a Tertiary Pediatric Intensive Care Unit.
- Dilek Cavusoglu, Elif Esra Sınmaz, Nihal Olgac Dundar, CanFulya KamitFKDepartment of Pediatric Intensive Care, Denizli Public Hospital, Denizli., Ayse Berna Anil, and Berrak Sarioglu.
- From the Department of Pediatric Neurology, Faculty of Medicine, Afyon Kocatepe University, Afyon.
- Pediatr Emerg Care. 2021 Jul 1; 37 (7): 360364360-364.
ObjectiveStatus epilepticus is associated with high rates of morbidity and mortality; thus, early diagnosis and proper treatment are crucial. We aimed to study the etiology, clinical features, and treatment among pediatric patients with convulsive status epilepticus.MethodsThe medical records of 100 patients were retrospectively obtained from pediatric intensive care unit. Etiology, clinical features, and treatment were interpreted by using Fisher exact test, χ2 test, and Spearman ρ correlation coefficient.ResultsSeizures had stopped with the first-, second-, and third-line treatment in 29%, 36%, and 35% of the patients, respectively. Only phenytoin treatment was efficient; it has 32.3% rate in second-line treatment. Whereas mortality rate was 10%, morbidity rate was 14% during the follow-up. Epilepsy, hemiparesis, spastic tetraparesis, and mental retardation developed. Mortality was significantly much more in the patients with refractory seizure and cerebral palsy. Development of mental retardation was much higher in the male sex.ConclusionsPhenytoin is still one of the most efficient antiepileptic drugs. If the duration of status epilepticus can be shortened by prompt treatment, neurological complications may be prevented.Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.
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