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Review Case Reports
Pathologically confirmed malignant syphilis using immunohistochemical staining: report of 3 cases and review of the literature.
- Paola Maldonado Cid, Elena Sendagorta Cudós, Francisco X Zamora Vargas, María José Beato Merino, and Pedro Herranz Pinto.
- From the Departments of *Dermatology, †Internal Medicine, and ‡Pathology, Hospital Universitario La Paz, Madrid, Spain.
- Sex Transm Dis. 2014 Feb 1; 41 (2): 94-7.
AbstractMalignant syphilis is a rare ulcerative variety. In the classical description of the disease, the absence of spirochetes in tissue samples was considered as a diagnostic criterion. We report 3 cases of malignant syphilis; in all of them, spirochetes were identified in cutaneous biopsy samples using immunohistochemical staining.
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