• Clin. Infect. Dis. · Jun 2002

    Case Reports

    Use of ventriculoperitoneal shunts to treat uncontrollable intracranial hypertension in patients who have cryptococcal meningitis without hydrocephalus.

    • Po-Chou Liliang, Cheng-Loong Liang, Wen-Neng Chang, Kang Lu, and Cheng-Hsien Lu.
    • Departments of 1Neurosurgery and 2Neurology, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Kaohsiung Hsien, Taiwan. chlu99@ms44.url.com.tw
    • Clin. Infect. Dis. 2002 Jun 15; 34 (12): E64-8.

    AbstractBetween 1997 and 2000, 4 human immunodeficiency virus-negative patients in our institution had cryptococcal meningitis with uncontrollable intracranial hypertension. All 4 patients were treated with antifungal drugs as well as ventriculoperitoneal (VP) shunts for intracranial hypertension. Neurological deficits that were unresponsive to pharmacologic treatment were resolved by use of the VP shunt. Uncontrollable elevation of intracranial pressure associated with cryptococcal meningitis can be resolved by use of a VP shunt, even when imaging studies do not reveal hydrocephalus.

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