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Obstetrics and gynecology · Oct 1997
Case ReportsIntravenous iron therapy for severe pregnancy anemia with high erythropoietin levels.
- N Carretti, M R Paticchio, and G A Eremita.
- Clinica Ostetrica e Ginecologica del'Università di Siena, Italy.
- Obstet Gynecol. 1997 Oct 1; 90 (4 Pt 2): 650-3.
BackgroundTo demonstrate that intravenous (IV) iron therapy rapidly can secure the physiologic correction of severe nonhemorrhagic anemia more safely than blood component therapy and recombinant erythropoietin treatment.CaseAn 18-year-old woman with beta-thalassemia in her 33rd week of gestation had a hemoglobin level of 4.8 g/dL and an erythropoietin value of 191 mU/mL. After IV iron administration, erythropoietin rapidly decreased and hemoglobin increased to 8.1 g/dL in correlation with estriol elevation. A healthy infant with normal hemoglobin and ferritin levels was delivered at 42 weeks by cesarean.ConclusionIntravenous iron administration rapidly corrected severe nonhemorrhagic anemia in a pregnant patient and may produce an improvement in fetal indices. High erythropoietin levels predict a good response to iron and may obviate the need for blood transfusions and recombinant erythropoietin administration, at least until this therapy is tried.
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