• Anesthesia and analgesia · Jul 2020

    Review

    Coronaviruses and SARS-CoV-2: A Brief Overview.

    • Stephan Ludwig and Alexander Zarbock.
    • From the Institute of Molecular Virology (IMV), University Hospital Münster, Münster, Germany.
    • Anesth. Analg. 2020 Jul 1; 131 (1): 939693-96.

    AbstractIn late December 2019, several cases of pneumonia of unknown origin were reported from China, which in early January 2020 were announced to be caused by a novel coronavirus. The virus was later denominated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and defined as the causal agent of coronavirus disease 2019 (COVID-19). Despite massive attempts to contain the disease in China, the virus has spread globally, and COVID-19 was declared a pandemic by the World Health Organization (WHO) in March 2020. Here we provide a short background on coronaviruses, and describe in more detail the novel SARS-CoV-2 and attempts to identify effective therapies against COVID-19.

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