• Behrouz Keleidari, Mohsen Mahmoudieh, Davarpanah Jazi Amir Hosein AH Minimally Invasive Surgery Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. , Hamid Melali, Farid Nasr Esfahani, Mohammad Minakari, and Mojgan Mokhtari.
• Minimally Invasive Surgery Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
• Obes Surg. 2019 Jun 1; 29 (6): 1721-1725.

IntroductionOne of the most acceptable procedures in bariatric surgery is laparoscopic gastric bypass. Laparoscopic Roux-en-Y gastric bypass (RYGB) is a common technique used in bariatric surgery. Recently, one anastomosis gastric bypass (OAGB) has been suggested as a simple, fast, and effective technique for obesity treatment. This study aims to compare the frequency of histologically proven bile reflux in OAGB and RYGB among patients with morbid obesity.MethodsThis prospective cohort study was performed from 2015 to 2017 in the Department of Bariatric Surgery of Isfahan University of Medical Sciences, Isfahan, Iran. Patients who had undergone RYGB or OAGB surgery were enrolled. Patients who had undergone revisional surgery were excluded. Data on demographics, symptoms, fasting blood sugar, lipid profile, endoscopic, and histologic findings (based on the Sydney bile reflux index) of bile reflux and postoperative complications were collected and compared for the two techniques.ResultsA total of 122 obese patients (22 males) who had undergone RYGB or OAGB surgery were included. The Sydney bile reflux index showed no statistically significant difference between RYGB and OAGB groups. Similarly, no statistically significant difference was found in the self-reported history of bile reflux-related symptoms, bile reflux markers in esophagogastroduodenoscopy, and postoperative complications between groups.ConclusionsOAGB and RYGB appear to be equal with respect to postoperative complications, bile reflux frequency, bile reflux index, and the Sydney system score.

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