• Pharmacoepidemiol Drug Saf · May 2017

    Sample size of the reference sample in a case-augmented study.

    • Palash Ghosh and Anup Dewanji.
    • Centre for Quantitative Medicine, Duke-National University of Singapore Medical School, Singapore.
    • Pharmacoepidemiol Drug Saf. 2017 May 1; 26 (5): 528-534.

    AbstractThe case-augmented study, in which a case sample is augmented with a reference (random) sample from the source population with only covariates information known, is becoming popular in different areas of applied science such as pharmacovigilance, ecology, and econometrics. In general, the case sample is available from some source (for example, hospital database, case registry, etc.); however, the reference sample is required to be drawn from the corresponding source population. The required minimum size of the reference sample is an important issue in this regard. In this work, we address the minimum sample size calculation and discuss related issues. Copyright © 2017 John Wiley & Sons, Ltd.Copyright © 2017 John Wiley & Sons, Ltd.

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