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- Federico Castillo-Álvarez, Ignacio Hernando de la Bárcena, and María Eugenia Marzo-Sola.
- Servicio de Neurología, Hospital San Pedro, Logroño, La Rioja, España. Electronic address: fcastilloa@riojasalud.es.
- Med Clin (Barc). 2017 Jan 6; 148 (1): 28-32.
IntroductionTrigeminal neuralgia is one of the most disabling facial pain syndromes, with a significant impact on patients' quality of life. Pharmacotherapy is the first choice for treatment but cases of drug resistance often require new strategies, among which various interventional treatments have been used. In recent years a new therapeutic strategy consisting of botulinum toxin has emerged, with promising results.DevelopmentWe reviewed clinical cases and case series, open-label studies and randomized clinical trials examining the use of botulinum toxin for drug-refractory trigeminal neuralgia published in the literature.ConclusionsThe administration of botulinum toxin has proven to be a safe and effective therapeutic strategy in patients with drug-refractory idiopathic trigeminal neuralgia, but many questions remain unanswered as to the precise role of botulinum toxin in the treatment of this disease.Copyright © 2016 Elsevier España, S.L.U. All rights reserved.
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