• Hongliang Zhang, Yugong Feng, Huanting Li, Bingke Lv, and Lin Wang.
• Department of Neurosurgery, the Affiliated Hospital of Qingdao University, Qingdao, China. Electronic address: zhlcmu@126.com.
• World Neurosurg. 2020 Jul 1; 139: 223-225.

BackgroundOsteosarcoma is a common malignant bone tumor that occurs in children or adolescents but rarely in the skull. Epidermoid cysts, also known as cholesteatomas, represent approximately 0.2%-1.8% of all intracranial tumors. The occurrence of osteosarcoma with an epidermoid cyst is extremely rare.Case DescriptionA 41-year-old woman had both osteosarcoma and cholesteatoma in the left cerebellopontine angle. We resected the 2 tumors using the suboccipital retrosigmoid approach, and she received radiotherapy and chemotherapy after the surgery. One year after surgery, the patient is healthy and has recovered well.ConclusionsOsteosarcomas and epidermoid cysts should be completely resected to prevent tumor recurrence and aseptic meningitis. Postoperative osteosarcoma treatment should include radiotherapy and chemotherapy to improve the survival rate of patients. It is hoped that this report will help clinicians in diagnosis and treatment of patients with similar conditions.Copyright © 2020 Elsevier Inc. All rights reserved.

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