• Fei Shao, Shuang Xu, Xuedi Ma, Zhouming Xu, Jiayou Lyu, Michael Ng, Hao Cui, Changxiao Yu, Qing Zhang, Peng Sun, and Ziren Tang.
• Beijing Key Laboratory of Cardiopulmonary Cerebral Resuscitation, Beijing Chaoyang Hospital, Beijing, China; Department of Emergency Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
• Resuscitation. 2020 Jun 1; 151: 182318-23.

ObjectiveTo describe the characteristics and outcomes of patients with severe COVID-19 and in-hospital cardiac arrest (IHCA) in Wuhan, China.MethodsThe outcomes of patients with severe COVID-19 pneumonia after IHCA over a 40-day period were retrospectively evaluated. Between January 15 and February 25, 2020, data for all cardiopulmonary resuscitation (CPR) attempts for IHCA that occurred in a tertiary teaching hospital in Wuhan, China were collected according to the Utstein style. The primary outcome was restoration of spontaneous circulation (ROSC), and the secondary outcomes were 30-day survival, and neurological outcome.ResultsData from 136 patients showed 119 (87.5%) patients had a respiratory cause for their cardiac arrest, and 113 (83.1%) were resuscitated in a general ward. The initial rhythm was asystole in 89.7%, pulseless electrical activity (PEA) in 4.4%, and shockable in 5.9%. Most patients with IHCA were monitored (93.4%) and in most resuscitation (89%) was initiated <1 min. The average length of hospital stay was 7 days and the time from illness onset to hospital admission was 10 days. The most frequent comorbidity was hypertension (30.2%), and the most frequent symptom was shortness of breath (75%). Of the patients receiving CPR, ROSC was achieved in 18 (13.2%) patients, 4 (2.9%) patients survived for at least 30 days, and one patient achieved a favourable neurological outcome at 30 days. Cardiac arrest location and initial rhythm were associated with better outcomes.ConclusionSurvival of patients with severe COVID-19 pneumonia who had an in-hospital cardiac arrest was poor in Wuhan.Copyright © 2020 Elsevier B.V. All rights reserved.

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