• Rikke Rousing, Andreas Ole Kirkegaard, Michael Nielsen, Eva Holtved, Leif Hougaard Sørensen, Thomas Lund, Viola Olesen, and Mikkel Ø Andersen.
• Center for Spine Surgery and Research, Lillebaelt Hospital, Oestre Hougvej 55, 5500, Middelfart, Denmark. rikke.rousing@rsyd.dk.
• Eur Spine J. 2020 Jul 1; 29 (7): 1573-1579.

PurposeTo summarize the recommendations from the national clinical guideline published by the Danish Health Authority, regarding cemental augmentation as treatment for painful vertebral lesions, in patients with malignant disease.MethodsA multidisciplinary working group formulated recommendations based on the GRADE approach.ResultsTwo of the questions were based on randomized studies and one on professional consensus. The guideline recommends cemental augmentation for painful vertebral lesions in patients with malignant diagnosis, either hematological or non-hematological. Fracture of the posterior wall is not a contradiction to cemental augmentation, but care should always be taken while injecting the cement, to decrease the risk of cemental leaks into the spinal canal.ConclusionThe recommendations are based on low-to-moderate quality of evidence or professional consensus as well as patient preferences and positive and harmful effects of the intervention. The working group recommends more randomized studies on patients with different malignant diseases and painful vertebral lesions comparing percutaneous vertebroplasty/kyphoplasty and conservative treatment to confirm the conclusion in this guideline. These slides can be retrieved under Electronic Supplementary Material.

15 keywords...

hide…