• Der Anaesthesist · Jul 2020

    Case Reports

    [Posterior reversible encephalopathy syndrome and hyperammonemia: two entities causing cerebral edema and status epilepticus in a female patient after lung transplantation].

    • F Bächle, J Bansbach, I Hettich, J Lambeck, Ö Senbaklavaci, and J Kalbhenn.
    • Klinik für Anästhesiologie und Intensivmedizin, Universitätsklinikum Freiburg, Hugstetter Straße 55, 79106, Freiburg, Deutschland.
    • Anaesthesist. 2020 Jul 1; 69 (7): 506-513.

    AbstractA 58-year-old woman developed rapidly progressive neurological symptoms and finally loss of vigilance 5 weeks following primarily successful lung transplantation. A posterior reversible encephalopathy syndrome (PRES) under treatment with tacrolimus as well as hyperammonemia due to sepsis with Ureaplasma urealyticum could be identified as the causes. Infections with Ureaplasma, bacteria which produce ammonia as a product of metabolism, are increasingly being identified in immunocompromised people by specific PCR (polymerase chain reaction) procedures and should routinely be taken into consideration as the cause of unspecific neurological symptoms.

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