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Case Reports
Unexpected Blood Pressure Sensitivity to Angiotensin II in a COVID-19 Patient with ARDS and Septic Shock.
- Hanyin Wang, Subhraleena Das, Patrick M Wieruszewski, Jamil Taji, Brian Bartlett, Nabila Azad, Arnab Chowdhury, Gururaj J Kolar, Nitesh Jain, Mir R Subla, and Syed Anjum Khan.
- Department of Hospital Internal Medicine, Mayo Clinic Health System, Mankato, MN.
- Chest. 2020 Aug 1; 158 (2): e55e58e55-e58.
AbstractWe report the case of an 88-year-old man with coronavirus disease 2019 (COVID-19) who presented with ARDS and septic shock. The patient had exquisite BP sensitivity to low-dose angiotensin II (Ang-2), allowing for rapid liberation from high-dose vasopressors. We hypothesize that sensitivity to Ang-2 might be related to biological effect of severe acute respiratory syndrome coronavirus 2 infection. The case is suggestive of a potential role for synthetic Ang-2 for patients with COVID-19 and septic shock. Further studies are needed to confirm our observed clinical efficacy.Copyright © 2020 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.
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