-
- Angela J Peck, E Claire Newbern, Daniel R Feikin, Elmira T Issakbaeva, Benjamin J Park, Jason Fehr, Ashley C LaMonte, Thong P Le, Terry L Burger, Luther V Rhodes, Andre Weltman, Dean Erdman, Thomas G Ksiazek, Jairam R Lingappa, and SARS Pennsylvania Case Investigation Team.
- National Center for Infectious Diseases, Division of Viral and Rickettsial Diseases, Respiratory and Enteric Virus Branch, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA. apeck@cdc.gov
- Emerging Infect. Dis. 2004 Feb 1; 10 (2): 217-24.
AbstractIn early April 2003, severe acute respiratory syndrome (SARS) was diagnosed in a Pennsylvania resident after his exposure to persons with SARS in Toronto, Canada. To identify contacts of the case-patient and evaluate the risk for SARS transmission, a detailed epidemiologic investigation was performed. On the basis of this investigation, 26 persons (17 healthcare workers, 4 household contacts, and 5 others) were identified as having had close contact with this case-patient before infection-control practices were implemented. Laboratory evaluation of clinical specimens showed no evidence of transmission of SARS-associated coronavirus (SARS-CoV) infection to any close contact of this patient. This investigation documents that, under certain circumstances, SARS-CoV is not readily transmitted to close contacts, despite ample unprotected exposures. Improving the understanding of risk factors for transmission will help focus public health control measures.
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