• Am J Emerg Med · Jul 2020

    Case Reports

    Pediatric perampanel poisoning.

    • Mariam Qozi and F Lee Cantrell.
    • California Poison Control System, 200 W. Arbor Drive, San Diego, CA 92103, USA. Electronic address: mqozi@calpoison.org.
    • Am J Emerg Med. 2020 Jul 1; 38 (7): 1545.e1-1545.e2.

    AbstractThere is no pediatric overdose information available for perampanel. We present twocases involving children 2 years of age. A female ingested 0.77mg/kg perampanel anddeveloped drowsiness and ataxia within an hour, followed by bradycardia after 6 hours.She was admitted to the pediatric intensive care unit and given fluids and was thendischarged after 20 hours. The other case involved a male who ingested 0.25mg/kgperampanel and developed ataxia within an hour, eventually he was discharged after 6hour observation in the emergency department without any treatment.Copyright © 2020 Elsevier Inc. All rights reserved.

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