• Leena Adamian, Ivan Urits, Vwaire Orhurhu, Dylan Hoyt, Rebecca Driessen, John A Freeman, Alan D Kaye, Rachel J Kaye, Andrew J Garcia, Elyse M Cornett, and Omar Viswanath.
• Creighton University School of Medicine, Omaha, NE, USA.
• Curr Pain Headache Rep. 2020 May 6; 24 (6): 27.

Purpose Of ReviewUrologic chronic pelvic pain syndrome (UCPPS) is a chronic, noncyclic pain condition which can lead to significant patient morbidity and disability. It is defined by pain in the pelvic region, lasting for greater than 3 to 6 months, with no readily identifiable disease process. The aim of this review is to provide a comprehensive update of diagnosis and treatment of UCPPS.Recent FindingsUCPPS encompasses chronic pelvic pain syndrome or chronic prostatitis (CP/CPPS) in men and interstitial cystitis or painful bladder syndrome (IC/PBS) in women. Underlying inflammatory, immunologic, and neuropathic components have been implicated in the pathogenesis of UCPPS. For optimal patient management, an individualized and multimodal approach is recommended. Medical management and physical therapy are the mainstays of treatment. Injection therapy may offer additional relief in medically refractory patients. Further minimally invasive management may include spinal cord and peripheral nerve stimulation, though evidence supporting efficacy is limited.

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