• Swiss medical weekly · Nov 2000

    Case Reports

    Hypokalaemic periodic paralysis associated with controlled thyrotoxicosis.

    • I Sabau and A Canonica.
    • Internal Medicine Department, Ospedale Civico, Lugano.
    • Swiss Med Wkly. 2000 Nov 4; 130 (44): 1689-91.

    AbstractFamilial hypokalaemic periodic paralysis is an autosomal dominant muscle disease which has been linked to point mutations in the skeletal muscle L-type calcium channel alpha 1 subunit (alpha 1 s). It consists of muscular weakness episodes due to hypokalaemia caused by intracellular shifting of potassium. We describe the case of a young man of Kurdish origin, with a history of Graves' disease, who was admitted to the emergency room with hypotonic tetraplegia associated with severe hypokalaemia.

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