• Darren A Chen, Avani S Vaishnav, Philip K Louie, Catherine Himo Gang, Steven J McAnany, Sravisht Iyer, Todd J Albert, and Sheeraz A Qureshi.
• Weill Cornell Medical College, New York, NY.
• Spine. 2020 Oct 15; 45 (20): 143514421435-1442.

Study DesignFollow-up study.ObjectiveTo determine whether minimally invasive lumbar spine surgery outcomes are different between those who are lost to follow-up and those who are not.Summary Of Background DataLost to follow-up patients are a common source of selection bias for clinical outcomes research. Currently, there are no US based studies that evaluate the differences in outcomes of lost to follow-up patients after spine surgeries.MethodsA retrospective review of prospectively collected data of 289 patients who underwent minimally invasive lumbar surgery and were at least 1 year postsurgery was performed. Patients were divided into two groups: (1) lost to follow-up (LTF), defined as patients who had missed more than two consecutive follow-up visits and had not attended their 1-year follow-up appointment; and (2) not lost to follow-up. For the not-LTF cohort, patient response outcome measures (PROMs) (oswestry disability index (ODI), visual analog scale (VAS) back/leg, Short Form-12 (SF-12) Physical/Mental, PROMIS) and return to activities data were collected prospectively at each follow-up. For LTF patients, data were collected through emailed surveys or telephone interviews. PROMs and return to activities data of the two groups were compared. Sub-group analysis by type of surgery (decompression or fusion) was also performed.ResultsFor the entire cohort, independent t test analysis showed LTF patients had greater improvement in PROMIS Physical Function scores than those who were not-LTF (15.08 vs. 10.38, P = 0.026). For fusion surgeries, LTF patients showed a greater improvement in ODI (-30.94 vs. -16.23, P = 0.003) VAS back (-4.92 vs. -2.99, P = 0.044), and PROMIS-PF (16.09 vs. 10.38, P = 0.049). There were no significant differences in complication rates between LTF and not LTF patients.ConclusionPatients undergoing minimally invasive lumbar surgery-in particular lumbar fusions-who are lost to follow-up and responded to subsequent email and phone interviews showed greater improvements in self-reported outcomes than those who continued to follow-up. Thus, our results suggest that a substantial subset of patients who are lost to follow-up do not fare worse than those who do follow-up. However, an opposite response cannot be excluded in those who did not respond to email and phone interviews.Level Of Evidence3.

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