• JNMA J Nepal Med Assoc · Jul 2019

    Case Reports

    Langerhan's cell Histiocytosis of Sphenoid Sinus causing Vision Loss: A Case Report.

    • Suresh Mani, Regi Thomas, Regi Mathew, and Rajiv Michael.
    • Department of ENT, Christian Medical College, Vellore, India.
    • JNMA J Nepal Med Assoc. 2019 Jul 1; 57 (218): 281-284.

    AbstractLangerhan's cell histiocytosis is an uncontrolled proliferation of dendritic cells. The involvement of skull base is rare. Variable clinical presentation and multi organ involvement often warrant a multidisciplinary approach for a successful diagnosis. We are reporting a case of 16-year-old male with sphenoid sinus Langerhan's cell histiocytosis which presented as a sudden and painless loss of vision. It is a rare entity in the diagnosis of blindness. Delayed diagnosis and treatment can result in serious complications. The radiological features and management options are discussed with a review of the pertinent literature. Keywords: : blindness; histiocytosis; langerhans-cell; sphenoid sinus.

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