• Aline Ramond-Roquin, Maud-Christine Chouinard, Bayero Boubacar Diallo, Tarek Bouhali, Sylvie Provost, and Martin Fortin.
• Family physician and postdoctoral fellow in the Department of Family Medicine and Emergency Medicine at the Université de Sherbrooke.
• Can Fam Physician. 2019 Aug 1; 65 (8): 559-566.

ObjectiveTo identify the mechanisms associated with success and failure of chronic disease prevention and management (CDPM) programs, as well as their key contexts.DesignRealist synthesis.SettingSix primary care CDPM programs funded between 2011 and 2013 in Quebec.ParticipantsPatients, health providers, program leaders, and other stakeholders involved in CDPM programs.MethodsA collaborative research process was implemented, involving representatives from the executive and advisory committees: researchers, health care providers, decision makers, and patients and families. Leaders were asked to provide all documents related to their programs to the research team. The documents were selected depending on their relevance and rigour. The thematic analysis of each program consisted of identifying the outcomes and mechanisms, as well as the specific contexts associated with these outcomes. Results for each program were validated by its leader before synthesizing the results of all programs together.Main FindingsA total of 108 documents (eg, grant applications, scientific reports) were collected from the programs. Positive and negative outcomes were observed at the patient, health care provider, and health care system levels. Four main mechanism categories were associated with outcomes: patient-centred interdisciplinary care; self-management support and a motivational approach; professional support; and care coordination and relationships with partners. The main contextual factors that influenced the successes of these mechanisms were related to patients (multimorbidity, involvement of family caregivers), to health care providers (professional training, culture of interprofessional collaboration, mobilization of family physician), and to health care organizations (coordination between services, history of collaboration between partners, funding).ConclusionThis study confirms the essential role of patient-centred interdisciplinary care; self-management support and a motivational approach; professional support; and care coordination and relationships with partners when caring for patients with chronic diseases. It constitutes a relevant contribution for stakeholders involved in primary care transformation and should be used to inform the sustainability and scaling up of CDPM programs.Copyright© the College of Family Physicians of Canada.

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