• Neth J Med · Sep 2019

    Review

    The value of FDG-PET CT scans to evaluate bone marrow in haemato-oncological conditions.

    • P M van Son, D Evers, and E H J G Aarntzen.
    • Radboud University, Nijmegen, the Netherlands.
    • Neth J Med. 2019 Sep 1; 77 (7): 234-242.

    AbstractIn the past decade, 18F-fluorodeoxyglucose positron emission tomography combined with computed tomography (18F-FDG PET-CT) scans have been increasingly implemented in the diagnostic process of several haemato-oncological conditions. Accurate assessment of bone marrow activity observed on 18F-FDG PET-CT is crucial for a correct diagnostic conclusion, subsequent treatment decision, and follow-up strategies. By systematically considering the arguments of the level of 18F-FDG uptake, distribution pattern, coinciding changes of the bone structure, and the clinical context, interpretation and validity may improve. This review aims to give a comprehensive overview of the different patterns of 18F-FDG uptake on PET/CT in common benign, clonal, and malignant haematological conditions, accompanied by illustrative cases.

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