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Internal medicine journal · Apr 2020
Performance of risk models predicting cardiac complications in pregnant women with congenital heart disease: a meta-analysis.
- WangTom Kai MingTKM0000-0002-4547-6892Paediatric and Congenital Cardiac Service, Starship Hospital, Auckland, New Zealand.Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand., Boris Lowe, Stephanie Hlohovsky, and Clare O'Donnell.
- Paediatric and Congenital Cardiac Service, Starship Hospital, Auckland, New Zealand.
- Intern Med J. 2020 Apr 1; 50 (4): 481484481-484.
AbstractAccurate risk stratification is important in pregnant women including the growing population with congenital heart disease (CHD). We meta-analysed the performance of risk models for CHD women. Six studies with 3426 pregnancies were studied, with cardiac complication rates of 6.7-20.6%. Pooled c-statistics (95% confidence interval) for scores were mWHO 0.71 (0.65-0.76), CARPREG 0.66 (0.61-0.71) and ZAHARA 0.71 (0.65-0.76). Current risk models had at best moderate discrimination for CHD women with significant room for improvement.© 2020 Royal Australasian College of Physicians.
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