• Jonatas Christian Vieira Moura, Isabel Cristina Gomes Moura, Guilherme Rache Gaspar, Guilherme Matos Serretti Mendes, Bernardo Almeida Vial Faria, Nulma Souto Jentzsch, Maria do Carmo Friche Passos, Amanj Kurdi, Brian Godman, and Alessandra Maciel Almeida.
• Programa de Pos Graduacao em Ciencias da Saude, Faculdade de Ciencias Medicas de Minas Gerais, Belo Horizonte, MG, BR.
• Clinics (Sao Paulo). 2019 Jan 1; 74: e950.

ObjectivesEvaluate the use of probiotics as an additional therapy in the treatment of children and adolescents with asthma in Belo Horizonte, MG-Brazil.MethodsA pilot longitudinal, experimental and nonrandomized study with 30 patients from six to 17 years old from Belo Horizonte. In the baseline appointment, all patients received beclomethasone, and one group also received a probiotic containing Lactobacillus reuteri (n=14). The patients were reassessed after at least 60 days with the Asthma Control Test, spirometry and self-report of the symptoms they experienced associated with asthma.ResultsA predominance of male patients (56.7%) and a mean age of 10.6 years were observed. The groups using probiotics did not differ in terms of sex, age or atopy. In the longitudinal evaluation, an increase in the Asthma Control Test scores and a reduction in the number of symptoms were observed in the probiotic group. There was an increase in the peak expiratory flow among those who used probiotics.ConclusionsThis pilot study supports the hypothesis that the administration of probiotics as a supplementary therapy for the treatment of children and adolescents with asthma improves the clinical condition of the patients. Further studies are needed to confirm the efficacy of probiotics in asthma treatment.

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