• Wien. Klin. Wochenschr. · Apr 2020

    Dengue and malaria infections in pregnancy : Maternal, fetal and neonatal outcomes at a tertiary care hospital.

    • Mujtaba Mubashir, Kaleem S Ahmed, Hadika Mubashir, Ayesha Quddusi, Ayesha Farooq, Sheikh Irfan Ahmed, Bushra Jamil, and Rahat Qureshi.
    • Aga Khan University Medical College, Karachi, Pakistan.
    • Wien. Klin. Wochenschr. 2020 Apr 1; 132 (7-8): 188-196.

    BackgroundMalaria and dengue cause major morbidity in developing nations and are more severe in pregnancy. Maternal, fetal, and neonatal outcomes in pregnant patients infected with dengue or malaria were studied.MethodsThe medical records of pregnant women admitted with either dengue or malaria infections from 2011-2015 to this hospital were reviewed. Clinical outcomes and laboratory tests were examined.ResultsOf 85 women, 56%, 21%, and 22% had contracted dengue, malaria, and multiple infections, respectively. Pregnant women who had contracted dengue fever alone were more likely to present to the hospital at an earlier gestational age (24 weeks, p = 0.03). Women with multiple infections, were more likely to deliver earlier (30 weeks, p < 0.01). Women with malaria were more likely to have low birth weight deliveries (mean birth weight 2394 g, p = 0.03). The incidence of in-hospital deaths among the cohort was 7%.ConclusionIt is imperative to develop guidelines to screen for and diagnose dengue and malaria in pregnancy.

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