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- Lawrence Tim Goodnough and Anil K Panigrahi.
- Department of Pathology, Stanford University, Stanford, CA, USA; Department of Medicine, Stanford University, Stanford, CA, USA. Electronic address: ltgoodno@stanford.edu.
- Med. Clin. North Am. 2017 Mar 1; 101 (2): 431-447.
AbstractTransfusion of red blood cells (RBCs) is a balance between providing benefit for patients while avoiding risks of transfusion. Randomized, controlled trials of restrictive RBC transfusion practices have shown equivalent patient outcomes compared with liberal transfusion practices, and meta-analyses have shown improved in-hospital mortality, reduced cardiac events, and reduced bacterial infections. This body of level 1 evidence has led to substantial, improved blood utilization and reduction of inappropriate blood transfusions with implementation of clinical decision support via electronic medical records, along with accompanying educational initiatives.Copyright © 2016 Elsevier Inc. All rights reserved.
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