• Cari Levy, Emily Galenbeck, and Kate Magid.
• Research, Rocky Mountain Regional Veterans Affairs Medical Center, Denver-Seattle Center of Innovation, 1700 North Wheeling Street, Aurora, CO 80045, USA; Division of Health Care Policy and Research, School of Medicine, University of Colorado, 1700 North Wheeling Street, Aurora, CO 80045, USA. Electronic address: https://twitter.com/cari_levy.
• Med. Clin. North Am. 2020 May 1; 104 (3): 471-489.

AbstractThe purpose of this article is to present evidence on the efficacy and safety of medical cannabis as a therapy for symptom management in palliative care. This article provides an overview of the evidence on the risks and benefits of using medical cannabis for the indications of chronic pain, cancer-related pain, cancer cachexia, dementia, and Alzheimer's disease. Currently, there is insufficient evidence to determine the effectiveness and safety of cannabinoids for most reviewed indications, with the exception of chronic pain. Future research is required before palliative care clinicians can make evidence-based decisions on the integration of medical cannabis as adjunct therapies.Copyright © 2020 Elsevier Inc. All rights reserved.

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