• Rev Med Interne · Aug 2019

    [Very early and early systemic sclerosis: An update].

    • M Michaud, F Catros, S Ancellin, and F Gaches.
    • Service de médecine interne, hôpital Joseph Ducuing, 15 rue de Varsovie, 31076 Toulouse, France. Electronic address: mmichaud@hjd.asso.fr.
    • Rev Med Interne. 2019 Aug 1; 40 (8): 517-522.

    AbstractClassification criteria for systemic sclerosis evolved over the last three decades, allowing an earlier classification. In the late 2000s, the EULAR Scleroderma Trials and Research Group validated very early and early systemic sclerosis criteria. Raynaud phenomenon, anti-nuclear antibody positivity and the puffy fingers are "Red flags" that must lead to refer the patient to a specialist and benefit from a capillaroscopy and the specific autoantibodies. At the stage of very early systemic sclerosis, pulmonary, cardiac and digestive involvements may be present and must be screened. Herein, we detail very early and early systemic sclerosis criteria, as well as the predictive factors of evolution towards a systemic sclerosis.Copyright © 2019 Société Nationale Française de Médecine Interne (SNFMI). Published by Elsevier Masson SAS. All rights reserved.

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