• Neuromodulation · Oct 2009

    Normalization of central cord syndrome spinal cord injury urodynamics after intrathecal baclofen therapy: a case report.

    • Adam L Schreiber, Guy W Fried, and Christopher S Formal.
    • Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA, USA; and Magee Rehabilitation, Philadelphia, PA, USA.
    • Neuromodulation. 2009 Oct 1;12(4):310-4.

    AbstractObjective. To report a case of improved urodynamics in a central cord syndrome spinal cord injury after intrathecal baclofen therapy. Methods. A 47-year-old man fell resulting in C4-C5 disc herniation with ventral spinal cord compression and cord edema. Results. He underwent an anterior cervical discectomy and fusion. Postoperatively, his examination revealed a C4 ASIA D injury in a central cord syndrome pattern. Cystometrogram (CMG) revealed a hyperactive detrusor with sphincter dyssynergia managed with intermittent self-catheterization. One and a half years later, he was impaired by severe lower limb spasticity, despite oral medications and botulinum toxin injections. After intrathecal pump therapy, CMG revealed relatively normal detrusor and minimal sphincter tone. He volitionally voids with urgency but improved continence, which was maintained in one-year follow-up. Conclusion. Although the main indication for intrathecal baclofen therapy is spasticity, improved urodynamics can be an additional benefit in central cord syndrome spinal cord injury.© 2009 International Neuromodulation Society.

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