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- Kinya Matsuo, Michiaki Koga, Mariko Oishi, Motoharu Kawai, and Takashi Kanda.
- Department of Neurology and Clinical Neuroscience, Yamaguchi University Graduate School of Medicine, Japan.
- Intern. Med. 2020 Jan 1; 59 (1): 119-120.
AbstractIsolated adrenocorticotropic hormone deficiency (IAD) is a cause of adrenal insufficiency (AI), which shows impaired secretion of adrenocorticotropic hormone (ACTH) with the preserved secretion of other anterior pituitary gland hormones. We herein report a case of IAD complicated by chronic thyroiditis presenting with neuropsychiatric symptoms without other signs indicative of AI that showed complete improvement of the cognitive function after the administration of corticosteroids. The clinical features of our case may be confused with autoimmune encephalopathies (AEs); however, IAD should be strictly differentiated from AEs, as it requires permanent hormone replacement without addition of immunosuppressive agents.
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