• Internal medicine · Jun 2020

    Review Case Reports

    Pulmonary Mycobacterium parascrofulaceum Infection in a Patient with Chronic Progressive Pulmonary Aspergillosis: A Case Report and Literature Review.

    • Hiroaki Ikegami, Kei Yamasaki, Toshinori Kawanami, Kazumasa Fukuda, Kentaro Akata, Midori Nakamura, Issei Ikushima, Yoko Fukuda, Shingo Noguchi, and Kazuhiro Yatera.
    • Department of Respiratory Medicine, University of Occupational and Environmental Health, Japan.
    • Intern. Med. 2020 Jun 1; 59 (11): 1417-1422.

    AbstractA 67-year-old man with a pulmonary cavity was admitted to our hospital. Mycobacterial culture of the bronchoalveolar lavage fluid sample obtained from the right upper pulmonary lesion tested positive for mycobacterium, and sequencing of the 16S rRNA genes, hsp65, and rpoB revealed that the cultured mycobacterium was Mycobacterium parascrofulaceum. Treatment with antimycobacterial agents was ineffective, and repeated culturing of bronchoscopic specimens revealed that the specimens were positive for Aspergillus fumigatus. Combination treatment of antimycobacterial agents and voriconazole improved the lung lesion. This is the first report of a patient with pulmonary M. parascrofulaceum infection complicated with chronic progressive pulmonary aspergillosis.

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