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- Mayuka Nishikawara, Toru Kawakami, Hitoshi Sakai, Fumihiro Kawakami, Sayaka Nishina, Takeshi Uehara, Fumihiro Ishida, and Hideyuki Nakazawa.
- Division of Hematology, Department of Internal Medicine, Shinshu University School of Medicine, Japan.
- Intern. Med. 2020 Jun 1; 59 (11): 1437-1443.
AbstractPrimary adrenal lymphoma (PAL) is rare and known to have a predilection for central nervous system (CNS) relapse. A 70-year-old man with a 2-year history of primary aldosteronism presented because of a fever. He was hypotensive, and his adrenal glands were unequivocally enlarged. PAL was diagnosed. Despite showing an initial response to immunochemotherapy, progressive paralysis ensued. Magnetic resonance imaging findings were negative, and rituximab was ineffective. His debilitated condition hindered further chemotherapy. A postmortem examination revealed lymphoma relapse in the systemic peripheral nerves. The sequential presentation of two rare lymphomas implies that PAL might have a predilection for not only the CNS but also peripheral nerves.
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