• J. Investig. Med. · Apr 2020

    Observational Study

    Risk factors concerning complications following permanent pacemaker implantation for patients on antithrombotic therapy: a cohort study.

    • Mª Reyes Carrión-Camacho, José Manuel Molina-Doñoro, and José Rafael González-López.
    • Clinical Management Unit-Anesthesiology and Resuscitation, Cardiac Surgery, Hospital Universitario Virgen del Rocío, Seville, Spain mariareyescarrioncamacho@gmail.com.
    • J. Investig. Med. 2020 Apr 1; 68 (4): 828-837.

    AbstractThe objective of this study was to identify the complications and associated factors presented by patients after pacemaker implantation, according to a regimen of antithrombotic therapy or without it. This is an analytical observational study on a prospective cohort of 310 consecutive patients with a permanent pacemaker implanted, included from January 1 to December 31, 2014 from 1 single center. The follow-up was conducted on 310 patients for 6 months. 239 patients (77%) received antithrombotic therapy at the time of the pacemaker implantation. 20.8% of complications are presented in patients without anticoagulant therapy, 80.8% of them being minor ones. In the case of patients with anticoagulant therapy, 30.3% of the complications are major ones. Factors associated with major complications were contusion (OR 2; 95% CI 1 to 3.8; p=0.049), and minor complications, arm immobilization >24 hours (p=<0.001) and contusion (p=0.002). This study found an increase in the overall risk and complications that can occur when implanting a permanent pacemaker in patients with antithrombotic therapy based on the time of immobilization and contusions after the implantation.© American Federation for Medical Research 2020. No commercial re-use. See rights and permissions. Published by BMJ.

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