• Aust Prescr · Dec 2019

    Review

    Penicillin allergy: a practical approach to assessment and prescribing.

    • Misha Devchand and Jason A Trubiano.
    • Antimicrobial Stewardship, Drug and Antibiotic Allergy Service and Centre for Antibiotic Allergy and Research, Austin Health, Melbourne.
    • Aust Prescr. 2019 Dec 1; 42 (6): 192-199.

    AbstractPenicillin allergies are not always lifelong. Approximately 50% are lost over five years A reaction to penicillin during a childhood infection is unlikely to be a true allergy Only 1–2% of patients with a confirmed penicillin allergy have an allergy to cephalosporins. In patients with a low risk of severe allergic reactions, cephalosporins are a relatively safe treatment option Patients with a history of delayed non-severe reactions, such as mild childhood rashes that occurred over 10 years ago, may be suitable for an oral rechallenge with low-dose penicillin. This should be done in a supervised hospital environment In many cases, with appropriate assessment and allergy testing, it may be possible to remove the penicillin allergy label(c) NPS MedicineWise 2019.

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