Gastrointestinal endoscopy
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Gastrointest. Endosc. · May 1988
Randomized Controlled Trial Comparative Study Clinical TrialMidazolam versus diazepam as premedication for upper gastrointestinal endoscopy: a randomized, double-blind, crossover study.
The effectiveness of midazolam as premedication for upper gastrointestinal endoscopy was examined and compared with that of diazepam in a double-blind crossover study involving 23 patients. The degree of sedation and cooperation of patients during the procedure and the speed of recovery from sedation were comparable for the two drugs. ⋯ Also, patients' acceptability for the procedure was significantly higher in the midazolam than in the diazepam group (78% vs. 26%). Therefore, when amnesia is desirable, as in the case of repeated endoscopies, midazolam should be the drug of choice.