Gastrointestinal endoscopy
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Gastrointest. Endosc. · Mar 2009
Randomized Controlled Trial Comparative StudyMidazolam with meperidine or fentanyl for colonoscopy: results of a randomized trial.
A combination of midazolam and opioid is usually used to achieve sedation and analgesia during colonoscopy. Two commonly used opioids are meperidine and fentanyl, but few studies have compared their efficacy. ⋯ The use of fentanyl in combination with low-dose midazolam results in significantly faster recovery from sedation compared with meperidine, without any apparent loss of analgesic effect.
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Gastrointest. Endosc. · Mar 2009
Randomized Controlled TrialCan wire-guided cannulation prevent post-ERCP pancreatitis? A prospective randomized trial.
Among the procedure-related factors associated with post-ERCP pancreatitis, selective cannulation of the common bile duct by insertion of a guidewire may be associated with fewer complications than conventional methods of cannulation with contrast injection to access the bile duct. However, the results of studies regarding the usefulness of wire-guided cannulation (WGC) are conflicting. ⋯ WGC is associated with a lower rate of post-ERCP pancreatitis. However, WGC may not prevent post-ERCP pancreatitis in patients with suspected SOD and unintentional PD guidewire cannulation.