Gastrointestinal endoscopy
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Gastrointest. Endosc. · Jul 2018
Randomized Controlled Trial Comparative StudyEfficacy of anterior versus posterior per-oral endoscopic myotomy for treating achalasia: a randomized, prospective study.
Per-oral endoscopic myotomy (POEM) has been demonstrated to be safe and effective for treating achalasia. Two approaches-anterior myotomy and posterior myotomy-are used during POEM. However, little is known about the comparison between the 2 different approaches. The objective of the study is to compare the safety and short-term efficacy of the 2 approaches for treating achalasia. ⋯ The short-term treatment efficacy, manometry outcomes, and adverse events were comparable between the anterior and posterior myotomy groups. Large-scale studies with long-term follow-up are warranted for a more definitive conclusion. (Clinical trial registration number: ChiCTR-ICR-15007211.).