Respiration; international review of thoracic diseases
-
Randomized Controlled Trial
The effects of controlled breathing during pulmonary rehabilitation in patients with COPD.
Conventional pulmonary rehabilitation programs improve exercise tolerance but have no effect on pulmonary function in patients with chronic obstructive pulmonary disease (COPD). The role of controlled breathing using respiratory biofeedback during rehabilitation of patients with COPD remains unclear. ⋯ In patients with COPD undergoing a pulmonary rehabilitation program, controlled breathing using respiratory biofeedback has no effect on exercise capacity, pulmonary function, quality of life or cardiac autonomic function.
-
Randomized Controlled Trial
Effects of adding omalizumab, an anti-immunoglobulin E antibody, on airway wall thickening in asthma.
Omalizumab may inhibit allergic inflammation and could contribute to decreasing airway remodeling in patients with asthma. ⋯ These findings suggest that omalizumab reduced airway wall thickness and airway inflammation. Larger patient studies with longer-term follow-up are needed to show whether omalizumab can truly maintain improved airway wall dimensions.