Respiration; international review of thoracic diseases
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Randomized Controlled Trial Comparative Study
Metabolic and respiratory variables during pressure support versus synchronized intermittent mandatory ventilation.
Mechanically ventilated patients interact and respond differently to different modes of ventilatory support. ⋯ Changes in the level of PSV resulted in smaller changes in metabolic and respiratory variables compared with equivalent changes in the level of volume-cycled SIMV support. PSV may be more suitable for progressive respiratory muscle reloading.
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Randomized Controlled Trial
Home-based exercise training as maintenance after outpatient pulmonary rehabilitation.
Pulmonary rehabilitation is successful in improving exercise capacity and quality of life in patients with chronic obstructive pulmonary disease (COPD). However, training effects diminish over time. ⋯ We demonstrated that training effects obtained from an outpatient rehabilitation program can be maintained by home-based exercise training in patients with moderate COPD.
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Randomized Controlled Trial
Preserving oxygenation during walking in severe chronic obstructive pulmonary disease: noninvasive ventilation versus oxygen therapy.
Physical activity is known to cause significant deoxygenation in patients with severe chronic obstructive pulmonary disease (COPD). Although noninvasive positive pressure ventilation (NPPV) has been shown to improve oxygenation and physical activity in these patients, no practical approach for the application of NPPV during walking has yet been established. ⋯ NPPV plus supplemental oxygen, but not oxygen alone, preserves oxygenation during walking in patients with severe COPD. However, dyspnea and walking distance were not improved due to the burden of carrying the heavy ventilatory equipment in a backpack.
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Randomized Controlled Trial
Efficacy of salbutamol and ipratropium bromide in the management of acute bronchiolitis--a clinical trial.
A wide range of drugs are commonly used to treat bronchiolitis, but evidence of their effectiveness is limited. ⋯ Clinical scores and oxygen saturation levels improved more rapidly in the bronchodilator groups than in the placebo group up to 24 h, but these drugs did not have a sufficient effect to change the natural course of the disease.
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Randomized Controlled Trial
Titration efficacy of two auto-adjustable continuous positive airway pressure devices using different flow limitation-based algorithms.
Auto-adjustable continuous positive airway pressure devices are widely used in titration procedures to determine therapeutic pressure levels in obstructive sleep apnea patients. However, differences in operational characteristics may influence the effect on the apnea-hypopnea index (AHI). ⋯ While the RR provided a lower AHI than the RS at lower pressure levels, it could not be assessed whether this difference was relevant for clinical outcomes. However, this face-to-face comparison of Auto-adjustable continuous positive airway pressure devices seems useful for the assessment of titration efficacy.