The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
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J. Matern. Fetal. Neonatal. Med. · Jul 2014
Alterations of natriuretic peptides amino-terminal pro B-type natriuretic peptide and amino-terminal pro C-type natriuretic peptide during the pregnancy.
The aim of this study was to determine the plasma levels of natriuretic peptides amino-terminal pro B-type natriuretic peptide (NT proBNP) and amino-terminal pro C-type natriuretic peptide (NT proCNP) during pregnancy and any possible changes occurring in each trimester. ⋯ This is the first study evaluating the longitudinal levels of NT proCNP during the pregnancy, and demonstrates that NT proCNP remained constant, but NT proBNP levels do not significantly alter during pregnancy.
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J. Matern. Fetal. Neonatal. Med. · Jun 2014
Randomized Controlled TrialUnsynchronized nasal intermittent positive pressure versus nasal continuous positive airway pressure in preterm infants after extubation.
To determine the effect of unsynchronized nasal intermittent positive pressure ventilation compared to continuous positive airway pressure in preterm infants after extubation. ⋯ NIPPV (although non-synchronized and delivered by single nasal prong) had a better effect than NCPAP after extubation of preterm infants on mechanical ventilation in respect to reducing the prevalence of post-extubation atelectasis, re-intubation and also death.
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J. Matern. Fetal. Neonatal. Med. · Jun 2014
Plasma anandamide and related n-acylethanolamide levels are not elevated in pregnancies complicated by hyperemesis gravidarum.
Cannabinoids are effective antiemetics and the "endogenous cannabinoids" (endocannabinoids) are thought to modulate emesis in both humans and animal models. Endocannabinoids, their receptors and their metabolising enzymes are present in peripheral blood and a reduction in blood endocannabinoid concentration has been observed in individuals with excessive nausea and vomiting following parabolic flight manoeuvres. We tested the hypothesis that plasma endocannabinoid levels are similarly perturbed in women with hyperemesis gravidarum (HG), a condition where the aetiopathogenesis is still unknown, compared to normal pregnant controls. ⋯ These results would suggest that either the circulating endocannabinoids quantified may not be key modulating factors in HG or that the expected endocannabinoid system response to the stress induced by nausea and vomiting of early pregnancy remain unchanged in women with HG.
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J. Matern. Fetal. Neonatal. Med. · May 2014
ReviewLung ultrasonography for the diagnosis of neonatal lung disease.
Ultrasound has recently become an important method for diagnostic examination and monitoring of lung disease. Many lung diseases, such as respiratory distress syndrome, transient tachypnea of the newborn, pneumonia, atelectasis and pneumothorax were diagnosed by chest X-ray or CT scan in the past, but can now easily be diagnosed with lung ultrasound. ⋯ It is therefore feasible and convenient to perform at the bedside in a neonatal ward. This review focuses on features of bedside lung ultrasound and diagnosis features of common lung diseases in newborn infants, culminating in suggestions for improving the application of ultrasound in the neonatal field.
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The reliability of pulse oximetry in the lower SaO2-ranges has not been fully investigated. We wanted to investigate pulse oximeter performance in a pig model of perinatal asphyxia. ⋯ Pulse oximetry was less reliable at SaO2-values below 60%. Tissue acidosis and reduced peripheral perfusion may have contributed to this. It is unknown whether the difference between SpO2 and SaO2 is clinically relevant.