Clinical physiology and functional imaging
-
Clin Physiol Funct Imaging · May 2003
Oxygen tension under hyperbaric conditions in healthy pig brain.
To investigate the effect of hyperbaric conditions on brain oxygenation, intracranial pressure and brain glucose/lactate levels in healthy non-brain-traumatized animals. ⋯ If there is a need for increased oxygenation in the brain, then one way to achieve this is to apply hyperbaric conditions at 100% oxygen. Compared with an atmospheric pressure with a FiO2 of 0.4, a nine-fold increase (900%) in PbrO2 values can be reached by increasing the FiO2 to 1.0 and the pressure to 2.8 bar. In this study, hyperbaric oxygen pressure in the brain did not lead to changes in intracranial pressure or in brain glucose/lactate levels.