Clinical physiology and functional imaging
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Clin Physiol Funct Imaging · Jul 2004
Brain glucose and lactate levels during ventilator-induced hypo- and hypercapnia.
Levels of glucose and lactate were measured in the brain by means of microdialysis in order to evaluate the effects of ventilator-induced hypocapnia and hypercapnia on brain metabolism in healthy non-brain-traumatized animals. ⋯ Hypocapnia decreases brain glucose and increases brain lactate concentration, indicating anaerobic metabolism, whereas hypercapnia has no influence on levels of brain glucose and brain lactate.