Clinical physiology and functional imaging
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Clin Physiol Funct Imaging · Mar 2007
ReviewLung protective ventilatory strategies in acute lung injury and acute respiratory distress syndrome: from experimental findings to clinical application.
This review addresses the physiological background and the current status of evidence regarding ventilator-induced lung injury and lung protective strategies. Lung protective ventilatory strategies have been shown to reduce mortality from adult respiratory distress syndrome (ARDS). ⋯ We describe a rational strategy, the open lung strategy, to accomplish an open lung, which may further prevent injury caused by mechanical ventilation. Finally, the clinician is offered directions on lung protective ventilation in the early phase of ARDS which can be applied on the intensive care unit.